Foundation
English
Conjunctions
Conjunctions
Conjunction
Question
Fill in the blank with a word(s) (a formal one) expressing contrast or concession in the following sentence:
_______________, in the goodness of her heart she laboriously spelled out her instructions to me in special lessons twice a week, to give Miss Gray a little rest.
In spite
But
Despite
Nonetheless
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Solution
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'Nonetheless' is used to show a contrast between two ideas. 'In spite' is used to express that something is unexpected or surprising. 'But' is used to contrast the ideas. 'Despite' is used to express that something is unexpected or surprising.
The given sentence shows the contrast between giving instructions and giving Miss Gray a little rest. 
Thus, option B is the correct answer.