Engineering
Chemistry
Tautomerism
Question

How many Hydrogen atoms are replaced by D in the following tautomerization.

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Solution

Tautomerization involves the migration of a hydrogen atom and switching of bonds. In keto-enol tautomerism, the enol form has acidic hydrogens attached to oxygen. When deuterium (D) is involved, it replaces these exchangeable hydrogens.

The enol form has one hydroxyl group (-OH) with one acidic hydrogen. During tautomerization, this hydrogen is replaced by deuterium. Therefore, only one hydrogen atom is replaced by D.

Final Answer: 1