Foundation
Biology Foundation
Heredity And Variation
Question

If the basic sequence of the strand of DNA is CAT TAG CAT CAT GAC. What will be base sequence of complementary RNA strand?

GUA  AUC GUA GUA CUG

GTA  ATG ATG GUA CUG

GTA  ACC GAT GAT CAT CAT

TAG  ATG GTA GAT GAT CTS

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Solution

Concept: DNA to RNA Transcription

DNA (Deoxyribonucleic acid) and RNA (Ribonucleic acid) are nucleic acids with complementary base pairing. In transcription, a complementary RNA strand is synthesized from a DNA template strand.

Base Pairing Rules:

  • DNA base Adenine (A) pairs with RNA base Uracil (U)
  • DNA base Thymine (T) pairs with RNA base Adenine (A)
  • DNA base Guanine (G) pairs with RNA base Cytosine (C)
  • DNA base Cytosine (C) pairs with RNA base Guanine (G)

This can be summarized as:

DNA: A RNA: U DNA: T RNA: A DNA: G RNA: C DNA: C RNA: G

Step-by-Step Solution:

Given DNA sequence: CAT TAG CAT CAT GAC

Step 1: Separate into codons for clarity: CAT - TAG - CAT - CAT - GAC

Step 2: Apply base pairing rules to each base:

  • C → G
  • A → U
  • T → A
  • T → A
  • A → U
  • G → C
  • C → G
  • A → U
  • T → A
  • C → G
  • A → U
  • T → A
  • C → G
  • A → U
  • T → A
  • G → C
  • A → U
  • C → G

Step 3: Write the complementary RNA sequence by grouping into codons:

GUA - AUC - GUA - GUA - CUG

Final Answer: GUA AUC GUA GUA CUG

Related Topics:

  • Central Dogma of Molecular Biology: Describes the flow of genetic information: DNA → RNA → Protein
  • Transcription: The process of copying a DNA sequence into RNA
  • Translation: The process of converting RNA sequence into amino acids to form proteins
  • Genetic Code: The set of rules by which information encoded in mRNA sequences is converted into proteins

Key Formulae and Rules:

Base Pairing Rules (DNA to RNA):

A U , T A , G C , C G

DNA Replication Base Pairing (DNA to DNA):

A T , T A , G C , C G