Grignard reagents (R-Mg-X) form from alkyl/aryl halides and Mg in ether. However, compounds with acidic protons (like -OH) or reactive groups (like carbonyls) will not form stable Grignard reagents because they react with the highly basic/nucleophilic reagent.

The first option, HO-CH₂-CH₂-CH₂-Cl, contains an acidic -OH group. This proton will react with the forming Grignard reagent in an acid-base reaction, preventing its formation.

The reaction would be: $\mathrm{HO}-R-\mathrm{Cl}+\mathrm{Mg}\underset{\mathrm{ether}}{\to }\mathrm{HO}-R-\mathrm{MgCl}\to R-H+\mathrm{Mg}\left(\mathrm{OH}\right)\mathrm{Cl}$

Final Answer: The first reaction (HO-CH₂-CH₂-CH₂-Cl) will not produce a Grignard reagent.