Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur ?

Medical

Biology

Cell Organization

Eukaryotic Cell

Mitosis

Question

Anaphase Promoting Complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is expected to occur ?

A

Recombination of chromosome arms will occur.

B

Chromosomes will not condense.

C

Chromosomes will be fragmented.

D

Chromosomes will not segregate.

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Anaphase promoting complex helps in the transition of the chromosome from metaphase to anaphase. The APC attaches to the chromosomes aligned at the equator during metaphase and allows the segregation of the chromatids.

So, the correct answer is option D.