Medical
Biology
Upper Respiratory Tract
Question
The given graph shows the results of the comparison of binding of human hemoglobin and myoglobin to oxygen at different oxygen pressures.
The greatest difference in oxygen saturation between hemoglobin and myoglobin takes place at which of the following pressure?
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Solution
The answer is option A i.e. "1kPa"
Oxygen and carbon dioxide concentrations are expressed as partial pressures (measured in kPa). Hemoglobin is a tetramer while myoglobin is a monomer. Myoglobin is an O2 storage protein, whereas hemoglobin is an O2 transport protein. The sigmoidal kinetics although it shows that hemoglobin reaches saturation at similar pressures to myoglobin.