Engineering
Chemistry
Conformational Isomerism
Basic Concepts of GOC
Basic concepts of organic chemistry
Question
Which of the following cyclic amine has lowest ΔG for inversion?
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Solution
More is the steric hindrance the N of amine, lesser is the ΔG for inversion because it has the least tendency to invert)
Most steric hindrance is in C. Therefore it has lowest ΔG for inversion.